Overview:
In 2030, 1 in 5 Americans will be over the age of 60, and, 1 in 6 people in the world will be aged 60 or older.
There is a significant amount of money being invested into anti-aging research and products. The global anti-aging market was valued at approximately $62.3 billion in 2022, and it is expected to grow significantly over the next few years. This growth is driven by an increasing demand for anti-aging products and treatments, as well as advances in medical technology that allow for more effective anti-aging solutions.
Many pharmaceutical and biotechnology companies are investing heavily in anti-aging research, with the goal of developing new therapies that can slow or reverse the aging process. Additionally, there is a growing market for cosmetic anti-aging products, such as creams, serums, and supplements, which are marketed as being able to reduce the visible signs of aging.
- It is important to note that while there are many products and treatments that claim to have anti-aging effects, not all of them are scientifically proven or safe.
- Please do some detailed research before trying new treatments or supplements. “If it sounds too good to be true, then it probably is.” Supplement suppliers have been found to mislabel ingredients and/or mislabeled ingredient quantities. As an example see: “Potentially dangerous doses of melatonin and CBD found in gummies sold for sleep” published in April, 2023.
Why this is important:
At the biological level, ageing results from the impact of the accumulation of a wide variety of molecular and cellular damage over time. We need to educate ourselves to do what we can to do to be healthy, stay healthy and age healthy. We generally only go to a doctor or clinic after we become sick. We should be proactive and look after our bodies so we avoid getting sick…we only have one body.
Dive a little deeper:
Here are a few non-commercial websites that are very up to date and educational in the field of gerontology, healthy aging, and anti-aging:
The Buck Institute
The first independent biomedical research institute in the world focused solely on aging.
“Our mission is to end the threat of age-related disease for this and future generations
We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.”
The Buck Institute has a free newsletter.
The Buck institute also has a free online course on “Introduction to the biology of aging”
…please learn about your body, take the course!
https://www.buckinstitute.org/
Fight Aging! Newsletter
Fight Aging! publishes science news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the free newsletter:
It is a must read.
Aging
Aging publishes research papers in all fields of aging research including but not limited, aging from yeast to mammals, cellular senescence, age-related diseases such as cancer and Alzheimer’s diseases and their prevention and treatment, anti-aging strategies and drug development and especially the role of signal transduction pathways such as mTOR in aging and potential approaches to modulate these signaling pathways to extend lifespan.
The journal aims to promote treatment of age-related diseases by slowing down aging, validation of anti-aging drugs by treating age-related diseases, prevention of cancer by inhibiting aging. Cancer and COVID-19 are age-related diseases.
Anti-aging drug:
Rapamycin – Off market anti-aging drug
Rapamycin is a naturally occurring compound that was first discovered in the 1970s by a Canadian scientist named Suren Sehgal. Sehgal and his team found the compound in a soil sample collected on Easter Island, which is also known as Rapa Nui in the local language. Rapamycin was initially studied for its ability to fight fungal infections, but researchers soon discovered that it had other interesting properties.
In the 1990s, scientists discovered that rapamycin could inhibit the activity of a protein called mTOR, which plays a key role in regulating cell growth and metabolism. By inhibiting mTOR, rapamycin was found to have anti-cancer properties and was subsequently tested as a cancer treatment. By inhibiting mTOR, rapamycin has been found to improve mitochondrial function, reduce inflammation, and improve the functioning of stem cells, among other benefits. These effects are believed to contribute to the anti-aging benefits of rapamycin.
Rapamycin has also been found to have other health benefits, including its ability to suppress the immune system, which makes it useful for preventing organ rejection after transplantation. It has been shown to extend lifespan in animal studies, and there is ongoing research to explore its potential as an anti-aging drug.
Today, rapamycin and its derivatives are used in a variety of medical applications, including as immunosuppressants, cancer treatments, and anti-aging therapies.
“Rapamycin News” Blog
A very informative blog with many members contributing their experiences of using Rapamycin.
Rapamycin is considered by many geroscience researchers to be the “gold standard” of anti-aging drugs; with lifespan improvement typically 15% to 30%, and as high as 37% when combined with another longevity drug “Acarbose”. While these results have been in animals, there are early indications that these benefits may also translate to people.
- If you are new to Rapamycin you likely have questions… such as:
- What has research shown about Rapamycin for healthy life extension?
- What age is the best to start Rapamycin?
- What are the benefits people are seeing with Rapamycin?
- What are the side effects people are seeing with Rapamycin?
- What are typical dosing levels people are taking of Rapamycin for longevity purposes?
- What are common food / drugs / supplements that can cause issues with Rapamycin?
- How do I get a rapamycin Prescription?
- How do I buy Rapamycin and what are good prices for Rapamycin?
- Can Rapamycin slow Skin Aging?
- Can Rapamycin help hair growth, reverse gray hair?
- What are people’s results so far with Rapamycin? What percentage keep taking it?
To get answers to these questions and many other see:
https://www.rapamycin.news/news
40 min YouTube video on Rapamycin and aging
“Rapamycin for Longevity Nov 18, 2022 Dr Robert Lufkin MD“
One of the earliest scientists behind the study of Rapamycin as an anti-aging supplement:
Mikhail V Blagosklonny is one of the first scientists to research Rapamycin as an anti-aging drug.
Dr. Blagosklonny now has over 100 studies and articles on PubMed regarding Rapamycin.
Here are three of his research papers worth reading:
- “From rapalogs to anti-aging formula” Mikhail Blagosklonny PMID: 28548953 2017 May 30
- “Rapamycin for longevity: opinion article” Mikhail Blagosklonny PMID: 31586989 October 4, 2019
- Doses and schedules of rapamycin for longevity: does aging exist or only age-related diseases? May 2, 2023
Dr. Blagosklonny is a member of the editorial board of the website “Aging.”