Antioxidants, Free radicals, Polyphenols, Flavonoids – why are they important?


Life is all about codependency.

Mother nature had a purpose when creating the human body as a miraculous thriving organism. Humans and plants are codependent as they have opposite processes of gas exchange. Humans breathe in oxygen and breathe out carbon dioxide, while plants take in carbon dioxide and release oxygen.

Humans and plants help each other to maintain that balance of oxygen and carbon dioxide in the atmosphere which is essential for life. Without plants, humans would not have enough oxygen to survive, and without humans, plants would not have enough carbon dioxide to perform photosynthesis.

As it is with breathing, so it is with the inner workings of our body, it’s all about codependency.

Human cells are the basic units of life that make up all the tissues and organs in our body. They perform the various functions that are essential for our survival and growth: converting nutrients into energy, producing hormones and enzymes, fighting infections, repairing damage, and communicating with other cells.

Human cells help each other by forming specialized groups that work together to perform a specific task. Muscle cells contract and relax to enable movement, nerve cells transmit signals to control our actions and sensations, blood cells transport oxygen and nutrients to different parts of the body, and immune cells protect us from harmful invaders.



Free Radicals

Free radicals are molecules that have an unpaired electron in their outer shell. This makes them highly reactive and unstable, as they are constantly trying to steal electrons from other molecules. This can create inflammation and damage cells and DNA. It is thought to be one of the causes of aging and disease.

Free radicals are produced naturally in the body as a byproduct of normal metabolism. They are also produced by exposure to toxins in the environment, such as cigarette smoke, air pollution, and ultraviolet radiation.

The body has several mechanisms for protecting itself from the damage caused by free radicals. These include antioxidants, which are molecules that can donate electrons to free radicals, neutralizing them and making them harmless.

However, the body’s antioxidant defenses can be overwhelmed by an excess of free radicals. This can lead to oxidative stress, which is a condition in which the body produces more free radicals than it can neutralize. Oxidative stress has been linked to a number of chronic diseases, including heart disease, cancer, Alzheimer’s disease, and Parkinson’s disease.

The body has its own natural mechanisms to neutralize and eliminate excess free radicals by creating its own antioxidants and enzymes, but the balance between free radical production and free radical elimination is crucial for maintaining health and preventing oxidative stress.

As we age, the body struggles to keep up this balance, so it is very important to keep up with consuming healthy foods that contain antioxidants as well as talking to your doctor about supplements.



Antioxidants

Antioxidants are molecules that inhibit oxidation, a chemical reaction that can damage cells. Oxidation is a natural process that occurs in the body when cells use oxygen to produce energy by mitochondria through the citric acid cycle. As previously mentioned, oxidation can also produce free radicals. Free radicals produce inflammation and damage DNA, proteins, and lipids, which can lead to cell death.

Antioxidants work by neutralizing free radicals or by preventing them from being formed in the first place. They can do this by donating electrons to free radicals, which makes the the free radicals more stable and less likely to cause damage. 

Benefits of Antioxidants

There are many different types of antioxidants, both natural and synthetic. Some of the most well-known natural antioxidants include vitamins such as C and E, beta-carotene, and polyphenols. Eating a diet rich in antioxidants has been linked to a number of health benefits.

  • Reduced risk of heart disease
  • Reduced risk of cancer
  • Reduced risk of stroke
  • Reduced risk of Alzheimer’s disease
  • Improved cognitive function
  • Improved immune function
  • Slows the aging process


Polyphenols

Polyphenols are a type of antioxidant and can act as anti-inflammatory agents, protecting the body from oxidative stress and inflammation. Polyphenols are a category of phytonutrients, which are chemical compounds found in plants that provide specific health benefits.

Benefits of polyphenols

  • Antioxidant activity
  • Anti-inflammatory activity 
  • Improved heart health
  • Reduced risk of cancer
  • Improved brain health


Flavonoids

Flavonoids are a subclass of polyphenols and are the most abundant polyphenols in the human diet. Flavonoids are not digested or absorbed like other nutrients, but rather broken down by gut bacteria and used to provide antioxidant, anti-inflammatory and anti-cancer properties.

Flavonoids are a class of plant compounds found in a variety of fruits, vegetables, and herbs and give many fruits, vegetables and flowers their bright colors.

Flavonoids are divided into six subtypes, each found in different foods and having different effects on the body. For example, flavanols may help with cardiovascular disease, flavones may help with inflammation, and flavonols may help with cancer prevention.

Overall Benefits of Flavonoids

Flavonoids able to cross the blood-brain barrier, which means that they can have a more direct effect on the brain. They help:

  • Reduce the risk of heart disease
  • Reduce the risk of cancer
  • Protect against neurodegenerative diseases
  • Improve cognitive function
  • Reduce inflammation
  • Regulate blood sugar levels
  • Boost the immune system
  • Promote healthy skin

Some of the best food sources of flavonoids include:

  • Fruits:  Berries, apples, citrus fruits, grapes, cherries, plums
  • Vegetables: Broccoli, onions, spinach, kale,  tomatoes, peppers
  • Legumes:   Beans, lentils, peas
  • Nuts and Seeds:   Almonds, walnuts, peanuts, sunflower seeds
  • Spices:   Turmeric, ginger, cinnamon
  • Beverages:   Tea, coffee, red wine


Flavonoids are divided into six subtypes, each found in different foods and having different effects on the body.

  1. Flavanols help treat conditions such as viral infections, diabetes, and liver disease.
  2. Flavan-3-ols act as antioxidant, anticarcinogen, cardio preventive, antimicrobial, anti-viral, and neuro-protective agents. 
  3. Flavones provide antioxidant, anti-inflammatory, and anti-microbial support and its anti-carcinogenic activity promotes apoptosis of cancer cells
  4. Flavanones have anti-inflammatory properties and help you manage weight and cholesterol.
  5. Isoflavones help keep hormones balanced in your body
  6. Anthocyanins benefits include antioxidative and antimicrobial activities, improve visual and neurological health, and protect against various non-communicable diseases


from Healthline.com

Which foods have the different flavonoids?

Many plant products contain dietary flavonoids. Here are the six flavonoid subtypes, and the foods that contain them.

Flavanols

These types of flavonoids are known for their antioxidant properties. They may help manage symptoms of cardiovascular disease. Flavanols are found in these foods:

  • onions
  • kale
  • grapes and red wine
  • tea
  • peaches
  • berries
  • tomatoes
  • lettuce
  • scallions
  • broccoli

Flavan-3-ols

Foods with these types of flavonoids are very rich in nutrients. They include:

  • white tea
  • green tea
  • oolong tea
  • black tea
  • apples
  • purple and red grapes
  • blueberries
  • strawberries
  • cacao and chocolate products

Flavones

Flavones are the pigments in blue and white flowering plants. They also work as a natural pesticide, protecting leaves from harmful insects.

Flavones may also help with inflammation in the body. You can find them in:

  • parsley
  • red peppers
  • celery
  • chamomile
  • peppermint

Flavanones

Flavanones are known for their anti-inflammatory properties. They may also help you manage your weight and cholesterol. Flavanones are found in these foods:

  • lemons
  • limes
  • oranges
  • grapefruit

Isoflavones

Isoflavones may help keep hormones balanced in your body. Isoflavonoids are mainly in:

  • soy
  • legumes

Anthocyanins

Anthocyanins are naturally produced pigments that give flowers their red, purple, and blue color. They’re predominantly found in the outer skin of berries and berry products like:

  • red and purple grapes
  • red wine
  • cranberries
  • blueberries
  • strawberries
  • blackberries
Source: Healthline.com Which foods have flavonoids?


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